What Is Mesotherapy? In Which Conditions Is It Used?

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Mesotherapy is an aesthetic operation used by Dr Michel Pistor in 1952. Today, it is used for many purposes, especially cellulite, stretch marks, spots, scars, hair treatment, skin renewal, anti-aging, sports injuries and various skin diseases.

The basis of mesotherapy is to stimulate and renew structures such as collagen and elastin under the skin. In this way, blood circulation in the area is increased, fat burning is accelerated and lymph circulation is regulated.

What Is Mesotherapy?

Mesotherapy is a widely used method in cosmetic dermatology and aesthetic treatment. It is a concept derived from the Latin words meso (middle) and terapi (treatment) and its Turkish equivalent is middle skin treatment.

In mesotherapy, various vitamins, minerals, enzymes and amino acids are injected into the middle layer of the skin. In this way, it is aimed to regulate blood circulation and lymph circulation and to eliminate regional problems.

The substances used in the procedure and the method of application are regulated according to the wishes and problems of the person.

What Does Mesotherapy Do?

In the mesotherapy procedure, different drug mixtures are used for the need, these drugs are evaluated according to the problematic area. Drug mixtures are arranged to be used alone or composed of different substances.

By administering the substances to the skin, elastin and collagen structures under the skin are stimulated. In this way, the circulatory system in the region is regulated and the immune system responds to these substances by renewing the skin.

It is important to use the correct ratio and content of drugs in mesotherapy application organised in sessions.

Human skin continues to regenerate until a certain age and produces the vitamins and minerals necessary for this on its own. However, after a certain age, this regeneration stops and as a result, some skin problems begin to appear.

In the mesotherapy process, these substances, which are the basic building blocks of the skin, are returned to the skin and thus the skin gains brightness, vitality and elasticity. Especially as we get older, it prevents the skin from losing its moisture content and becoming dry and wrinkled. It treats skin cells by renewing them. It also renews the protein and amino acid structures under the skin and ensures that these structures nourish the skin.

In Which Cases Is Mesotherapy Applied?

Mesotherapy is a method that is generally applied to everyone and the aim of this method is to eliminate age-related, visually disturbing problems. Anyone suffering from problems such as wrinkles, sagging, cellulite and hair loss can have mesotherapy. However, it is not recommended for individuals under the age of 20.

Mesotherapy, which aims to restore the lost abilities of the skin by applying in many different situations, is often applied in the following cases:

  • Sun spots
  • Skin wrinkles and sagging
  • Under-eye bags, wrinkles around the eyes
  • Stretch marks and cellulite
  • Weight loss
  • Hair loss and baldness
  • Sports injuries
  • Allergies
  • Pigment deficiency in the skin
  • Fibromyalgia problem
  • Chronic and acute pain
  • Rheumatic and vascular disorders

Apart from these, mesotherapy is not suitable for

  • Pregnant women
  • Breastfeeding mothers
  • Those with a history of stroke
  • Diabetics requiring insulin use
  • People with blood clotting problems
  • Cancer patients
  • Urticaria patients
  • Heart patients taking more than one medication
  • Those at risk of having an allergic reaction to some of the substances to be applied in the procedure

How Is Mesotherapy Performed?

In mesotherapy, various substances must be injected into the middle layer of the skin to renew the structures and accelerate circulation. For this purpose, a solution specific to the relevant area and personal needs is prepared and injected with fine needles.

The main purpose of mesotherapy is to eliminate problems such as poor blood circulation and inflammation that cause skin damage. Therefore, the solution formula used in each application may be different from the other. Many vitamins, minerals, amino acids and plant extracts are used together.

Before the procedure, an anaesthetic cream is applied to the skin to numb the area. After the pain and pain sensation in the numb area is minimised, the application is started. During the procedure, very thin and skin-compatible needles are used. In this way, the specially prepared solution is given under the skin.

Mesotherapy is a method that is organised in sessions and planned according to the results of the person. Most applications take 3 to 6 sessions, but the number of sessions can be rearranged according to the need. The duration of the session varies between 15 and 30 minutes, in addition, it is necessary to wait for a while for the anaesthetic cream to take effect.

In addition, after the procedure, a 10-minute radiotherapy can be applied to relax the application area and increase the effectiveness of the solution. In general, the fact that there are many types of mesotherapy closely affects the application method and session times.

What Are The Types Of Mesotherapy?

Mesotherapy has many types according to the needle injection technique and application area. It is also divided into two according to the application method as needle and needle-free.


This method, also known as stem cell therapy, allows the skin to gain substances such as vitamins, minerals and amino acids required by hair follicles. The solution used in this procedure contains special drugs that accelerate capillary circulation and organic materials that nourish the epithelial tissue.

The whole mixture is injected into the middle layer of the skin, thus nourishing the hair follicles. At the same time, tissue damage in the hair follicles is removed and hair loss is prevented in this way.


Pain mesotherapy is a technique that relieves regional pain by affecting the mesoderm, the middle layer of the skin.

This method, which is applied in the form of injections with very fine-tipped needles, corrects the main problems that cause poor circulation and skin damage. The use of different solutions to solve the problems of different patients makes pain mesotherapy a therapeutic technique.

By injecting active substances into the problematic skin surface, problems in tissues such as skin, muscles and joints can be eliminated directly. In pain mesotherapy applications, the drug is applied locally and has a very slow spread. In this way, it leaves high-level and long-lasting positive effects.

It is also less invasive and requires fewer sessions than most other pain treatment methods. This method, which has very few drug-related side effects, does not adversely affect the person’s work life and daily life. The main ailments in which it is used are as follows:

  • Muscle and joint pain
  • Hand and wrist pains
  • Ligament and tendon injuries
  • Rheumatic and degenerative disorders
  • Meniscus
  • Neuralgias
  • Trigger finger
  • Acute and chronic tissue damage
  • Intestinal spasms
  • Migraine
  • Skin problems such as baldness and acne
  • Cellulite


In addition, pain mesotherapy is not recommended for acute infections, pregnancy, open wounds, heart attack risks, irregular hypertension and drug allergies. For this reason, it is important to evaluate the treatment details and session order together with the specialist physician’s recommendation.


This method is also known as mesolift and is a technique used against aging problems. The signs of aging on the facial skin are caused by the loss of elasticity of the skin and start as fine lines and wrinkles. Over time, these wrinkles deepen and sagging of the skin occurs. Facial mesotherapy accelerates skin metabolism with a special solution. Revitalising, regenerating and structuring substances important for the skin are injected into the middle layer. In this way, the skin is enabled to form excess collagen and the elastic ability is increased. Thanks to the increased oxygen density, the skin has a brighter, more vibrant and refreshed appearance within a few sessions. In addition, the skin tightens and gains strength in this way.



This method, which can be performed by people of all ages, aims to eliminate the orange peel appearance caused by circulatory problems. Cellulite problem is usually caused by hormonal factors and occurs with lymph drainage problems. In cellulite mesotherapy, lymph circulation is regulated, fat deposits accumulated under the skin are dissolved and hardened connective tissues are stretched. In this way, the cellulite appearance formed by the combination of fat and connective tissues is eliminated. In this procedure, which lasts for an average of 4 to 10 weeks, successful results can be obtained with weekly sessions. In some individuals, additional diet and exercise applications should also be planned.


Regional fat accumulated in the waist, abdomen, arms and legs are removed with this method. Regional fat mesotherapy has been developed as an alternative to liposuction method. It is applied by injecting a special solution into the problem area and in this way, the fat deposits accumulated under the skin are broken down. Supporting the procedure with a suitable diet and exercise helps to show much faster results.


This method is generally used for wrinkle reduction, facial rejuvenation, moisture balance, body tightening and hair treatment. Unlike other methods, the application is performed without the use of needles, so the risk of side effects on the skin is minimised. In needle-free mesotherapy, various devices that show meso peeling effect and provide skin renewal are used, but studies show that needle mesotherapy is much faster and more effective than this method.

After Mesotherapy Session

Mesotherapy does not affect the daily life of the person in any way, regardless of which area it is applied. Since it is an aesthetic method, it is possible to start work and complete daily tasks after the session. However, it is important to pay attention to some issues after mesotherapy.

  • Since the procedure is applied through needles, blood thinners should not be used before and after the session.
  • After the session, the application area should be kept dry for about 10-15 minutes.
  • Tight clothes that stick to the body should not be worn.
  • Strenuous movements should not be performed for an average of 48 hours after the session.

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